Shelli Graham Selected Research

Dyspareunia

9/2017	Visual improvements in vaginal mucosa correlate with symptoms of VVA: data from a double-blind, placebo-controlled trial.
8/2017	Patient acceptability and satisfaction with a low-dose solubilized vaginal estradiol softgel capsule, TX-004HR.
5/2017	A vaginal estradiol softgel capsule, TX-004HR, has negligible to very low systemic absorption of estradiol: Efficacy and pharmacokinetic data review.
1/2017	The REJOICE trial: a phase 3 randomized, controlled trial evaluating the safety and efficacy of a novel vaginal estradiol soft-gel capsule for symptomatic vulvar and vaginal atrophy.
1/2017	Consistency of Effect with a Low-Dose, Estradiol Vaginal Capsule (TX-004HR): Evaluating Improvement in Vaginal Physiology and Moderate-to-Severe Dyspareunia in Subgroups of Postmenopausal Women.
1/2017	TX-004HR vaginal estradiol has negligible to very low systemic absorption of estradiol.
12/2016	TX-004HR Improves Sexual Function as Measured by the Female Sexual Function Index in Postmenopausal Women With Vulvar and Vaginal Atrophy: The REJOICE Trial.
5/2015	The effect of renal and hepatic impairment on the pharmacokinetics of ospemifene, a tissue-selective estrogen agonist/antagonist.
4/2014	Assessment of ospemifene or lubricants on clinical signs of VVA.

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Shelli Graham Research Topics

Disease

13	Atrophy 01/2019 - 04/2014
9	Dyspareunia 09/2017 - 04/2014
3	Endometrial Hyperplasia 01/2020 - 01/2018
2	Endometrial Neoplasms (Endometrial Cancer) 01/2019 - 01/2019
1	Hemorrhage 01/2020
1	Amenorrhea 01/2020
1	Metrorrhagia (Spotting) 01/2020
1	Neoplasms (Cancer) 01/2019
1	Obesity 01/2019
1	Hyperplasia 01/2019
1	Pruritus (Itching) 05/2017
1	Purpura 04/2014

Drug/Important Bio-Agent (IBA)

8	TX-004HRIBA 09/2017 - 12/2016
7	Estradiol (Delestrogen)FDA LinkGeneric 01/2020 - 01/2017
7	Capsules (Microcapsules)IBA 01/2020 - 01/2017
4	Estrogens (Estrogen)FDA Link 01/2019 - 05/2015
2	Progesterone FDA LinkGeneric 01/2020 - 01/2018
2	Progestins (Progestagens)IBA 01/2019 - 01/2019
2	OspemifeneIBA 05/2015 - 04/2014
1	TX-001HRIBA 01/2020
1	antineoplaston A10 (A 10)IBA 01/2019
1	Hormones (Hormone)IBA 01/2019
1	Conjugated (USP) Estrogens (Premarin)FDA Link 01/2019
1	Tamoxifen FDA LinkGeneric 01/2019
1	Contraceptive Agents (Contraceptives)IBA 01/2019
1	Estrogen ReceptorsIBA 04/2014

Therapy/Procedure

2	Therapeutics 01/2019 - 01/2017